Neuromuscular Junction Case Study Question
Assignment ID Number AFFGEHU83939HD Type of Document Essay Writing Format APA/MLA/Harvard Academic Level Masters/University References/Sources 4 References
Neuromuscular Junction Case Study Question
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Muscular System: Neuromuscular Junction
1.Where Calcium stores in each muscle cell? _________________________
2.Synaptic vesicles in the axon terminal of a motor neuron contain what neurotransmitter? _________________________
3.An action potential in the axon terminal of a motor neuron opens what type of ion channels? _________________________
4.By what means of membrane transport does the neurotransmitter leave the axon terminal? _________________________
5.Binding of neurotransmitter to the receptors on the motor end plate opens what type of ion channels? _________________________
6.Opening of these channels leads to _________________________ of the motor end plate.
7.How is the neurotransmitter removed from the synaptic cleft?
8.As a result of question 6, an action potential is propagated along the sarcolemma of the muscle cell and down the _________________________ into the cell.
9.The result of this action potential releases what ion from the terminal cisternae of the SR? _________________________
Muscular System: Sliding Filament Theory
1.a. The thick filament is composed of what molecule? _________________________
- Flexing the head of this molecule provides what is known as the _________________________.
2.The myosin head contains binding sites for what two molecules?
3.Three molecules make up the thin filament.
- Which molecule has a binding site for myosin heads? _____________________
- Which molecule covers this binding site? __________________________________________
- Which molecule has a binding site for calcium ions? ______________________________
4.What molecule must bind to the myosin head in order for it to disconnect with actin? _________________________
5.Breaking down of ATP or ___________of the ATP returns the myosin molecule to the high energy conformation.
6.Binding of the __________heads sequentially prevents backsliding of the thin filament.
7.Name three roles for ATP in the contraction of muscle.
8.What molecule is connected to the Z line? __________________________________
9.Which of the following shorten during contraction? (may be more than one)
- thin filament
- thick filament
Muscular System: Contraction of Motor Units
1.Define a motor neuron: _______________________________________________________________________________________________________________________________________________ _________
2.Define a motor unit: __________________________________________________________________________________________________________________________________________________________
3.The synapse between a motor neuron and the muscle it innervates is called a/an __________________________.
- The stimulation of additional motor units will increase the strength of the contraction. This process is called _______________________.
5.The muscles of the eye need to make precise small motor movements. Therefore, you would find________ (large or small) motor units in the eye.The muscles of the thigh exhibit gross movements for walking. Therefore, you would find_______ (large or small) motor units in the thigh.
6.a. How is muscle tone maintained in the muscle? ____________________________________________________________________________________________________________________
- If the nerve to a muscle is cut, what will happen to the muscle? _______________________________________________________________________________________________________ ___________
Muscular System: Contraction of Whole Muscle
1.Which of the following contract in an all-or-none fashion?
- whole muscle
- single muscle fiber
2.The development of tension in a muscle, in response to a stimulus above threshold, is called a/an _______________________________.
3.Identify the three phases of a muscle twitch from the following definitions:
- Sarcomeres shorten _______________________________
- Sarcomeres return to resting length _______________________________
- Sarcomeres at resting length _______________________________
4.a. Summation results from: _________________________________________________________________________________________________________________________________________
- In summation, you must __________ (Increase or decrease) the time interval between stimuli.
5.Below is a list related to summation. Put them in the correct order and describe each
Order Stage Description Fatigue Incomplete tetanus Treppe Complete tetanus
6.In the Motor Unit related section, how many motor units (many or few) were required to lift the weights when:
- the weight is very heavy (~50 lbs)? ______________________
- the weight was (~20 lbs)? _______________________
QUALITY OF RESPONSE NO RESPONSE POOR / UNSATISFACTORY SATISFACTORY GOOD EXCELLENT Content (worth a maximum of 50% of the total points) Zero points: Student failed to submit the final paper. 20 points out of 50: The essay illustrates poor understanding of the relevant material by failing to address or incorrectly addressing the relevant content; failing to identify or inaccurately explaining/defining key concepts/ideas; ignoring or incorrectly explaining key points/claims and the reasoning behind them; and/or incorrectly or inappropriately using terminology; and elements of the response are lacking. 30 points out of 50: The essay illustrates a rudimentary understanding of the relevant material by mentioning but not full explaining the relevant content; identifying some of the key concepts/ideas though failing to fully or accurately explain many of them; using terminology, though sometimes inaccurately or inappropriately; and/or incorporating some key claims/points but failing to explain the reasoning behind them or doing so inaccurately. Elements of the required response may also be lacking. 40 points out of 50: The essay illustrates solid understanding of the relevant material by correctly addressing most of the relevant content; identifying and explaining most of the key concepts/ideas; using correct terminology; explaining the reasoning behind most of the key points/claims; and/or where necessary or useful, substantiating some points with accurate examples. The answer is complete. 50 points: The essay illustrates exemplary understanding of the relevant material by thoroughly and correctly addressing the relevant content; identifying and explaining all of the key concepts/ideas; using correct terminology explaining the reasoning behind key points/claims and substantiating, as necessary/useful, points with several accurate and illuminating examples. No aspects of the required answer are missing. Use of Sources (worth a maximum of 20% of the total points). Zero points: Student failed to include citations and/or references. Or the student failed to submit a final paper. 5 out 20 points: Sources are seldom cited to support statements and/or format of citations are not recognizable as APA 6th Edition format. There are major errors in the formation of the references and citations. And/or there is a major reliance on highly questionable. The Student fails to provide an adequate synthesis of research collected for the paper. 10 out 20 points: References to scholarly sources are occasionally given; many statements seem unsubstantiated. Frequent errors in APA 6th Edition format, leaving the reader confused about the source of the information. There are significant errors of the formation in the references and citations. And/or there is a significant use of highly questionable sources. 15 out 20 points: Credible Scholarly sources are used effectively support claims and are, for the most part, clear and fairly represented. APA 6th Edition is used with only a few minor errors. There are minor errors in reference and/or citations. And/or there is some use of questionable sources. 20 points: Credible scholarly sources are used to give compelling evidence to support claims and are clearly and fairly represented. APA 6th Edition format is used accurately and consistently. The student uses above the maximum required references in the development of the assignment. Grammar (worth maximum of 20% of total points) Zero points: Student failed to submit the final paper. 5 points out of 20: The paper does not communicate ideas/points clearly due to inappropriate use of terminology and vague language; thoughts and sentences are disjointed or incomprehensible; organization lacking; and/or numerous grammatical, spelling/punctuation errors 10 points out 20: The paper is often unclear and difficult to follow due to some inappropriate terminology and/or vague language; ideas may be fragmented, wandering and/or repetitive; poor organization; and/or some grammatical, spelling, punctuation errors 15 points out of 20: The paper is mostly clear as a result of appropriate use of terminology and minimal vagueness; no tangents and no repetition; fairly good organization; almost perfect grammar, spelling, punctuation, and word usage. 20 points: The paper is clear, concise, and a pleasure to read as a result of appropriate and precise use of terminology; total coherence of thoughts and presentation and logical organization; and the essay is error free. Structure of the Paper (worth 10% of total points) Zero points: Student failed to submit the final paper. 3 points out of 10: Student needs to develop better formatting skills. The paper omits significant structural elements required for and APA 6th edition paper. Formatting of the paper has major flaws. The paper does not conform to APA 6th edition requirements whatsoever. 5 points out of 10: Appearance of final paper demonstrates the student’s limited ability to format the paper. There are significant errors in formatting and/or the total omission of major components of an APA 6th edition paper. They can include the omission of the cover page, abstract, and page numbers. Additionally the page has major formatting issues with spacing or paragraph formation. Font size might not conform to size requirements. The student also significantly writes too large or too short of and paper 7 points out of 10: Research paper presents an above-average use of formatting skills. The paper has slight errors within the paper. This can include small errors or omissions with the cover page, abstract, page number, and headers. There could be also slight formatting issues with the document spacing or the font Additionally the paper might slightly exceed or undershoot the specific number of required written pages for the assignment. 10 points: Student provides a high-caliber, formatted paper. This includes an APA 6th edition cover page, abstract, page number, headers and is double spaced in 12’ Times Roman Font. Additionally, the paper conforms to the specific number of required written pages and neither goes over or under the specified length of the paper.
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Neuromuscular Junction Case Study Question
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